Author

Patrick D. Skog

Scripps Research InstituteORCID 0000-0002-5759-5071Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 2 Approach:deep learning· 1 Assay:imaging· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Alessia LiguoriiD· 3 shared Oleksandr KalyuzhniyiD· 3 shared Ryan D. TingleiD· 3 shared William R. SchiefiD· 3 shared Andrew B. WardiD· 2 shared Claudia T. FlynniD· 2 shared Danny LuiD· 2 shared Jeong Hyun LeeiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

Alessia LiguoriORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ImmunologyProceedings of the National Academy of SciencesPeer-reviewedApr 7, 2026

Deep learning-enabled scaffolding of spatial arrays of PfCSP epitopes

Nelson R. Wu, Karla M. Castro, Nathan Beutler…·William R. Schief

This study uses deep learning to design multi-epitope scaffolds mimicking CSP's spatial structure, showing accurate positioning of two epitopes and partial success with the third.

DOI 10.1073/pnas.2521914123

deep learningprotein structure prediction

𝕏 PostBluesky

ImmunologySciencePeer-reviewedFeb 5, 2026

✦ In-depth digest

DNA origami vaccines program antigen-focused germinal centers

Anna M. Romanov, Grant A. Knappe, Larance Ronsard…·Darrell J. Irvine

DNA origami particles displaying eOD-GT8 with a synthetic T helper epitope gave antigen-focused germinal centers and expanded VRC01-class precursors in humanized mice after one immunization.

46 citationstop 1%

mouseimaging

𝕏 PostBluesky

ImmunologybioRxivPreprintMay 2, 2025

Virus glycoprotein nanodisc platform for vaccine design

Kimmo I. Rantalainen, Alessia Liguori, Gabriel Ozorowski…·William R. Schief

The paper presents a nanodisc platform for assembling transmembrane glycoproteins into vaccine candidates, demonstrating its utility in HIV vaccine development through structural and functional analyses.

3 citations

experimental assaydrug response / drug discovery

𝕏 PostBluesky