This study investigates the association between OXA-1 and TEM-1 genes and piperacillin/tazobactam resistance in ESBL-producing E. coli and K. pneumoniae across three U.S. military hospitals.

bioRxiv · Apr 18, 2025 · PreprintMicrobiology

Regional Plasmodium falciparum subpopulations and malaria transmission connectivity in Africa were detected with an enlarged panel of genome-wide microsatellite loci

Martha Anita Demba, Edwin T. Kamau, Jaishree Raman, Karim Mané, Lucas Emenga-Etego, Tobias Apinjo, Deus Isheghoma, Lemu Golassa, Oumou Maïga‐Ascofaré, Anita Ghansah, Marielle Karine Bouyou-Akotet, William Yavo, Milijoana Randrianarivelojosia, Fadel Diop, Eniyou Cheryll Oriero, , Alfred Amambua‐Ngwa

The paper identifies regional subpopulations and gene flow patterns of Plasmodium falciparum in Africa using genome-wide microsatellite loci from 992 isolates.

bioRxiv · Mar 8, 2024 · PreprintGenomics

Evidence of interaction between humoral immunity and drug half-life in determining treatment outcome for artemisinin combination therapy in high transmission settings in western Kenya

Ben M. Andagalu, Pinyi Lu, Irene Onyango, Elke S. Bergmann‐Leitner, Ruth Wasuna, Geoffrey Odhiambo, Lorna J. Chebon, Luicer Anne Olubayo Ingasia, Dennis W. Juma, Benjamin Opot, Agnes C. Cheruiyot, Redemptah A. Yeda, Charles Okello Okudo, Raphael O. Okoth, Gladys C. Chemwor, , Edwin T. Kamau

The paper investigates how humoral immunity interacts with drug half-life to affect treatment outcomes for artemisinin combination therapies in western Kenya.

Frontiers in Medicine · Oct 13, 2022Peer-reviewedBioinformatics