Henning Seedorf

Comparative analysis of adhesin-like proteins from Methanobacteriales species

The paper analyzes adhesin-like proteins (ALPs) in Methanobacteriales species to understand their role in gut microbiota interactions and species-specific adaptations.

Sequence-independent protein domain detection and classification with PRISM

PRISM enables sequence-independent, one-shot fine-tuning for simultaneous protein domain segmentation and classification, improving accuracy for complex and novel architectures.

GuFi phages represent the most prevalent viral family-level clusters in the human gut microbiome

The paper identifies GuFi phages as prevalent gut viral families using long-read sequencing and shows their broad host ranges and underappreciated impact on the microbiome.

High-throughput single-cell isolation of Bifidobacterium strains from the gut microbiome

This paper evaluates a high-throughput single-cell dispensing platform for isolating Bifidobacterium strains from fecal samples, demonstrating its effectiveness in recovering diverse, novel bacterial isolates.

Comparative genomics of DH5α-inhibiting Escherichia coli isolates from human feces reveals common co-occurrence of bacteriocin genes with virulence factors and antibiotic resistance genes.

This study identifies bacteriocin genes co-occurring with antibiotic resistance and virulence factors in gut E. coli, highlighting their role in microbial dynamics and resistance dissemination.

Dissecting the heat stress altering immune responses and skin microbiota in fish in a recirculating aquaculture system in Singapore

The paper investigates how heat stress affects immune responses and skin microbiota in farmed fish in Singapore's recirculating aquaculture system.

Genome-centric analysis of short and long read metagenomes reveals uncharacterized microbiome diversity in Southeast Asians

The paper uses long-read and Hi-C technologies to analyze gut microbiomes from Southeast Asians, revealing novel species, improved references, and uncharacterized biosynthetic gene clusters.