Inducible genome-wide mutagenesis for improvement of pDNA production by E. coli
Zidan Li, George Sun, Ibrahim S. Al’Abri, Yi‐Hui Zhou, Nathan Crook
This study develops an E. coli strain with enhanced plasmid DNA production through genome-wide mutagenesis and identifies key genetic factors contributing to increased plasmid copy numbers.
Microbial Cell Factories · Aug 13, 2025Peer-reviewedSynthetic Biology