Anne Van Arsdale

The paper uses genomic tools to analyze HPV-human DNA integration structures in a cancer cell line, revealing complex intrachromosomal and extrachromosomal architectures.

The paper develops a tool to detect viral integrations in human genomes and applies it to over 30,000 tumor samples, identifying virus-human chimeric transcripts and insertion hotspots.

FusionInspector identifies and characterizes biologically relevant fusion transcripts from RNA-seq data in tumor and normal tissues using clustering and machine learning.