BioinformaticsFundamental ResearchPeer-reviewed
Multiple conformational states assembly of multidomain proteins using evolutionary algorithm based on structural analogues and sequential homologues
Chunxiang Peng, Xiaogen Zhou, Jun Liu…·Guijun Zhang
This paper introduces M-SADA, an evolutionary algorithm for modeling multiple conformational states of multidomain proteins, showing improved performance over AlphaFold2 on benchmark datasets.