Perfect adaptation achieved by transport limitations governs the inorganic phosphate response in S. cerevisiae.
Hon Ming Yip, Shiyu Cheng, Evan J. Olson, Michael A. Crone, Sebastian J. Maerkl
The paper identifies a robust, perfectly adapted Pho regulon state in S. cerevisiae under intermediate Pi conditions and proposes transport limitations as the mechanism for adaptation.
bioRxiv · May 26, 2022 · PreprintSystems Biology