Author

David Pekker

University of PittsburghORCID 0000-0002-5873-0028Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Fabrisia AmbrosioiD· 1 shared Gabrielle G. GilmeriD· 1 shared Juliana BergmanniD· 1 shared Kai Wang· 1 shared Meghan McGraw· 1 shared Michel ModoiD· 1 shared Monica McArthuriD· 1 shared Sara Yanke· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Fabrisia AmbrosioORCID

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2 papers

Recent·Most cited

A Dose-Response Model for Accurate Detection and Quantification of Transcriptome-Wide Gene Knockdown for Oligonucleotide-Based Medicines

David Pekker, Steven Kuntz, Monica McArthur, T. Nicholson-Shaw, Sara Yanke, Swagatam Mukhopadhyay

The paper develops a dose-response model and analysis tool to accurately quantify gene knockdown effects of oligonucleotide-based medicines using next-generation sequencing data.

bioRxiv · May 28, 2024 · PreprintPharmacology & Toxicology

Mapping the landscape of magnetic field effects on neural regeneration and repair: a systematic review, mathematical model, and meta-analysis

Meghan McGraw, Gabrielle G. Gilmer, Juliana Bergmann, Vishnu Seshan, Kai Wang, David Pekker, Michel Modo, Fabrisia Ambrosio

This paper evaluates how magnetic fields affect neural repair in vitro through systematic review, mathematical modeling, and meta-analysis, finding increased NPC proliferation and decreased astrocytic differentiation.

bioRxiv · Mar 14, 2023 · PreprintNeuroscience