The DNA replication protein Orc1 from the yeast Torulaspora delbrueckii is required for heterochromatin formation but not as a silencer-binding protein
The paper investigates the evolutionary transition of Orc1 to Sir3 in yeast by studying Orc1's role in heterochromatin formation in Torulaspora delbrueckii, showing it spreads without silencer-binding.
Genetics · Jul 27, 2022Peer-reviewedGenetics