Molecular BiologybioRxivPreprint
Functional profiling reveals a non-enzymatic role of NUDT5 in repressing purine de novo synthesis
Jung-Ming G. Lin, Anh Tuấn Nguyễn, Anne-Sophie M. C. Marques…·Stefan Kubicek
The paper identifies a non-enzymatic role of NUDT5 in repressing purine de novo synthesis by scaffolding PPAT, with implications for cancer treatment and MTHFD1 deficiency.
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