Author

Jung-Ming G. Lin

Austrian Academy of SciencesORCID 0000-0002-3260-5544Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Jung-Ming G. Lin1 paper

Biology Disciplines

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Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Andreas BergthaleriD· 2 shared Anna KoreniD· 2 shared J. Thomas HannichiD· 2 shared Jakob‐Wendelin GengeriD· 2 shared Kristaps KlavinsiD· 2 shared Stefan KubicekiD· 2 shared Alexander LercheriD· 1 shared Anh Tuấn NguyễniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersImmunology

Andreas BergthalerORCID

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2 papers

Recent·Most cited

Purine nucleobases enhance CD8+ T cell effector function

Jakob‐Wendelin Genger, Ben Haladik, Alexander Lercher, Benedikt Agerer, Carolina Mangana, Fabian Amman, Csilla Viczenczová, Theresa Hohl, Anna Hofmann, Maximilian Koblischke, Bernhard Kratzer, Wentao Li, Kerstin Zinober, Felix Kartnig, Christina Schüller, , Andreas Bergthaler

This study identifies purine nucleobases as immunometabolites that enhance CD8+ T cell effector function by enabling a metabolic switch from de novo synthesis to salvage pathway.

bioRxiv · Aug 14, 2025 · PreprintImmunology

Functional profiling reveals a non-enzymatic role of NUDT5 in repressing purine de novo synthesis

Jung-Ming G. Lin, Anh Tuấn Nguyễn, Anne-Sophie M. C. Marques, Lorenzo Scrofani, Diana Daum, Ludwig G. Bauer, Carol Cheng, Luna D’Angelo, Juan Sánchez-Ávila, Christoph Bueschl, Pisanu Buphamalai, Marton I. Siklos, Jakob‐Wendelin Genger, Gerald Hofstätter, Kathrin Runggatscher, , Stefan Kubicek

The paper identifies a non-enzymatic role of NUDT5 in repressing purine de novo synthesis by scaffolding PPAT, with implications for cancer treatment and MTHFD1 deficiency.

bioRxiv · Mar 16, 2025 · PreprintMolecular Biology