Liskin Swint‐Kruse

RheoScale 2.0 identifies protein positions with varied substitution outcomes, revealing roles beyond neutral or deleterious, improving interpretation of high-throughput mutagenesis data.

The paper experimentally separates the effects of amino acid substitutions on function and abundance for SARS-CoV-2 Mpro, revealing their distinct contributions to DMS outcomes.

The paper identifies an evolutionary pathway between two protein folds using statistical methods and structural models on bacterial response regulator proteins.

The paper compares in vitro and in vivo activities of engineered LacI-based repressor proteins, showing that DNA looping and operator sequence variation significantly affect their function.