Molecular BiologybioRxivPreprint
An anti-aggregation region of the SGS3 N-terminal IDR is essential for secondary siRNA biogenesis
Yuji Fujimoto, Yuriki Sakurai, Ryosuke Kowada…·Hiro‐oki Iwakawa
This study identifies two functional modules in the N-terminal IDR of SGS3, showing that the NCR is critical for secondary siRNA production while the PrLD is involved in phase separation.
DOI 10.64898/2026.01.02.697351