Author

Naiduwadura Ivon Upekala De Silva

University of Alabama at BirminghamORCID 0000-0002-5937-0271Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Erin PowelliD· 1 shared Jun ZhangiD· 1 shared Peter E. Prevelige· 1 shared Talia FargasoniD· 1 shared Trenton M. PauliD· 1 shared Zihan ZhangiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

Erin PowellORCID

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1 paper

Recent·Most cited

Controlled by disorder: phosphorylation modulates SRSF1 domain availability for spliceosome maturation

Talia Fargason, Erin Powell, Naiduwadura Ivon Upekala De Silva, Trenton M. Paul, Zihan Zhang, Peter E. Prevelige, Jun Zhang

This study shows phosphorylation of SRSF1's RS domain modulates its interactions with RRM1 and RNA, affecting spliceosome maturation and phase separation.

Protein Science · Feb 19, 2025Peer-reviewedBiochemistry