BiochemistryProtein SciencePeer-reviewed
Controlled by disorder: phosphorylation modulates SRSF1 domain availability for spliceosome maturation
Talia Fargason, Erin Powell, Naiduwadura Ivon Upekala De Silva…·Jun Zhang
This study shows phosphorylation of SRSF1's RS domain modulates its interactions with RRM1 and RNA, affecting spliceosome maturation and phase separation.
8 citations