Author

Sanjana Saravanan

MRC London Institute of Medical SciencesORCID 0000-0002-5974-7710Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Anno I KoetjeiD· 1 shared David RuedaiD· 1 shared Graeme A. KingiD· 1 shared Luis AragoniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperMolecular Biology

Anno I KoetjeORCID

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1 paper

Recent·Most cited

Negative supercoiling facilitates human TOP3α-mediated decatenation of DNA braids via catenation junction melting

Sanjana Saravanan, Anno I Koetje, Graeme A. King, David Rueda, Luis Aragon

The paper shows that negative supercoiling enables TOP3α to resolve DNA braids by melting crossings into single-stranded DNA, facilitated by TRR and RPA.

bioRxiv · Sep 24, 2026 · PreprintMolecular Biology