NeuroscienceCellPeer-reviewed
The structural basis for LRRK2's activation and autoinhibition
Amalia C. Villagran Suarez, Kathryn S. Hatch, Tatyana Bodrug…·Andrés E. Leschziner
This paper elucidates the structural mechanisms by which LRRK2 is activated and autoinhibited, showing how mutations affect these processes and suggesting therapeutic strategies.
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