Author
University of California San DiegoORCID 0009-0000-8023-5720Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
3 papers
Recent·Most cited
Amalia C. Villagran Suarez, Kathryn S. Hatch, Tatyana Bodrug…·Andrés E. Leschziner
This paper elucidates the structural mechanisms by which LRRK2 is activated and autoinhibited, showing how mutations affect these processes and suggesting therapeutic strategies.
Siyu Chen, Tamar Basiashvili, Joshua Hutchings…·Elizabeth Villa
This study uses cryo-ET to show that LRRK2 can form microtubule-bound filaments in its autoinhibited state, with structural differences compared to active-LRRK2 filaments.
Tiantai Ma, Erica Xiong, Rea M. Lardelli, Jens Lykke‐Andersen
This study identifies how TOE1 selectively processes snRNAs by recognizing Sm complex assembly and 5' cap trimethylation, distinguishing them from other small non-coding RNAs.