Author

Charles J. Dorman

Trinity College DublinORCID 0000-0002-6018-9170Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Aalap MogreiD· 1 shared Carsten KrögeriD· 1 shared Craig J. BenhamiD· 1 shared Erwin van DijkiD· 1 shared Frédéric BoccardiD· 1 shared Mickaël BourgeiD· 1 shared Mounia KortebiiD· 1 shared Penn Faulkner RainfordiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiophysics

Aalap MogreORCID

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2 papers

Recent·Most cited

TORCphysics: A physical model of DNA-topology-controlled gene expression

Victor Velasco-Berrelleza, Penn Faulkner Rainford, Aalap Mogre, Craig J. Benham, Charles J. Dorman, Carsten Kröger, Susan Stepney, Sarah Anne Harris

This paper introduces a physical model called TORCphysics that simulates DNA supercoiling-mediated gene expression regulation using genome architecture inputs.

Nucleic Acids Research · Feb 4, 2026Peer-reviewedBiophysics

Bacterial chromatin remodeling associated with transcription-induced domains at pathogenicity islands

Mounia Kortebi, Mickaël Bourge, Romain Le Bars, Erwin van Dijk, Charles J. Dorman, Stéphanie Bury‐Moné, Frédéric Boccard, Virginia S. Lioy

The paper investigates how SPI-1 activation in Salmonella remodels chromatin structure and regulates gene expression through H-NS and HilD interactions.

Nature Communications · Jan 8, 2026Peer-reviewedMicrobiology