Stéphanie Bury‐Moné

This study relocates a gene cluster to the central chromosomal compartment in Streptomyces, enhancing its transcription and antibiotic production without altering chromosome compaction.

This paper introduces a new integrative tool, Samy, for targeting the terminal compartment of Streptomyces chromosomes, expanding genetic engineering capabilities.

The paper investigates how SPI-1 activation in Salmonella remodels chromatin structure and regulates gene expression through H-NS and HilD interactions.

SYNTERUPTOR identifies genomic islands containing specialised metabolite gene clusters in microbial genomes, detecting clusters missed by existing tools.

The paper shows that ribosomal RNA operons in Streptomyces define a central functional compartment in the chromosome, with dense core genes and high expression levels.