GeneticsPLoS GeneticsPeer-reviewed
Tulp3 quantitative alleles titrate requirements for viability, brain development, and kidney homeostasis but do not suppress Zfp423 mutations in mice.
Corinne A. McCoy, Dorothy Concepcion, Mark G. Mezody…·Bruce A. Hamilton
The paper creates a Tulp3 quantitative allelic series in mice to determine the dose-response effects of TULP3 on viability, brain development, and kidney disease, finding limited genetic interaction with Zfp423 mutations.
DOI 10.1371/journal.pgen.1011911