Kent C. Berridge

This study shows that mesocorticolimbic stimulation can control motivation for opioids like remifentanil or sucrose, similar to how it controls cocaine motivation, by pairing stimulation with reward.

The paper uses optogenetic stimulation in rats to confirm two cortical hedonic hotspots in orbitofrontal cortex and insula that enhance sweetness liking and identify a suppressive hedonic coldstrip.

This study investigates how different subregions of the rat olfactory tubercle modulate hedonic reactions to sucrose using pharmacological microinjections and behavioral assays.

This study uses optogenetics to map functional differences in subregions of the rat lateral hypothalamus, finding that tuberal LH promotes food intake but shifts toward self-stimulation with repeated stimulation.