Mathematical modeling unveils the timeline of CAR-T cell therapy and macrophage-mediated cytokine release syndrome
Daniela Silva Santurio, Luciana Rodrigues Carvalho Barros, Ingmar Glauche, Artur C. Fassoni
The paper develops a mathematical model to analyze the timeline of CAR-T cell therapy and macrophage-mediated cytokine release syndrome, identifying key mechanisms and parameters influencing treatment outcomes.
PLoS Computational Biology · Apr 9, 2025Peer-reviewedSystems Biology