Healthy B cells: allies or adversaries of CAR-T cell immunotherapy?
Emanuelle Arantes Paixão, Luciana Rodrigues Carvalho Barros, Artur C. Fassoni, Regina C. C. Almeida
This paper develops a mathematical model to study how healthy B-cells affect CAR-T cell therapy outcomes in B-cell cancers, showing their variable impact based on patient-specific factors.
Computers in Biology and Medicine · Aug 6, 2025Peer-reviewedCancer Biology