Optical Pooled Screening for the Discovery of Regulators of the Alternative Lengthening of Telomeres Pathway
Isabel Quintanilla, Benura Azeroglu, Md Abdul Kader Sagar, Travis H. Stracker, Eros Lazzerini Denchi, Gianluca Pegoraro
The paper develops an Optical Pooled Screen (OPS) assay using telomeric native DNA FISH to measure ALT pathway activity and identifies regulators of the ALT pathway.
Methods · Feb 16, 2025Peer-reviewedCell Biology