Spatial Transcriptomics of IPMN Reveals Divergent Indolent and Malignant Lineages
Matthew K. Iyer, Ashley A. Fletcher, Jude Ogechukwu Okoye, Chanjuan Shi, Fengming Chen, Elishama N. Kanu, Austin M. Eckhoff, Matthew Bao, Marina Pasca di Magliano, Timothy L. Frankel, Arul M. Chinnaiyan, Daniel P. Nussbaum, Peter J. Allen
This paper uses spatial transcriptomics to identify low-risk and high-risk expression programs in IPMN that correlate with exocrine and basal-like PDAC signatures, improving risk stratification.
Clinical Cancer Research · Feb 19, 2025Peer-reviewedCancer Biology