Chanjuan Shi

This study shows that NNK induces acute DNA damage and chronic HR repair dysregulation in pancreatic cells, linked to genomic instability and poor prognosis in PDAC.

This study identifies PDAC cancer cell subpopulations using multiplexed glycan immunofluorescence and shows consistent aberrant glycan signatures in both tumor and blood samples, improving detection beyond CA19-9 alone.

This paper uses spatial transcriptomics to identify low-risk and high-risk expression programs in IPMN that correlate with exocrine and basal-like PDAC signatures, improving risk stratification.