NeurosciencebioRxivPreprint
Inhibition of CGRP receptor ameliorates AD pathology by reprogramming lipid metabolism through HDAC11/LXRβ/ABCA1 signaling
Guangchun Fan, Fangzheng Chen, Min Liang…·Fang Huang
This study shows that inhibiting the CGRP receptor reduces AD pathology by reprogramming lipid metabolism via the HDAC11/LXRβ/ABCA1 signaling pathway in both human and mouse models.