Tilen Koklič

The paper pre-validates an animal-free method, InfiniteLungDT, which predicts chronic neutrophilic lung inflammation using in vitro data, achieving high accuracy in LOAEL determination.

This study shows that particulate matter exposure in vitro causes amyloid beta plaques and neurite shortening in neuron-like cells, resembling Alzheimer's disease features.

The paper predicts nanomaterial-induced chronic inflammation using in vitro measurements and in silico modeling by identifying mechanisms of nanomaterial cycling and quarantining in lung cells.