TidyMass2: Advancing LC-MS Untargeted Metabolomics Through Metabolite Origin Inference and Metabolic Feature-based Functional Module Analysis
Xiao Wang, Yijiang Liu, Chao Jiang, Zinuo Huang, Hong Yuan Yan, Sunny Hei Wong, Caroline Helen Johnson, Jingxiang Zhang, Yun Ge, Feifan Zhang, Junli Zhang, Renfu Lai, Peng Gao, Xuebin Zhang, Xiaotao Shen
TidyMass2 improves untargeted metabolomics by inferring metabolite origins and analyzing functional modules, increasing biologically interpretable features from 5.8% to 58.8% in pregnancy urine data.
Nature Communications · Jan 17, 2026Peer-reviewedBioinformatics