Author

Hong Yuan Yan

Hong Kong Baptist UniversityORCID 0000-0002-4059-6625Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:metabolomics· 2 Research Focus:cell-cell communication· 1 Research Focus:database / resource· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Caroline Helen JohnsoniD· 2 shared Carmen Chak‐Lui WongiD· 1 shared Chao JiangiD· 1 shared Feifan ZhangiD· 1 shared Hiu‐Lok NganiD· 1 shared Jacinth Wing‐Sum CheuiD· 1 shared Jingxiang Zhang· 1 shared Junli ZhangiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioinformatics

Caroline Helen JohnsonORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BioinformaticsNature CommunicationsPeer-reviewedJan 17, 2026

TidyMass2: Advancing LC-MS Untargeted Metabolomics Through Metabolite Origin Inference and Metabolic Feature-based Functional Module Analysis

Xiao Wang, Yijiang Liu, Chao Jiang…·Xiaotao Shen

TidyMass2 improves untargeted metabolomics by inferring metabolite origins and analyzing functional modules, increasing biologically interpretable features from 5.8% to 58.8% in pregnancy urine data.

12 citationstop 1%

humanmetabolomics

𝕏 PostBluesky

Systems BiologybioRxivPreprintAug 6, 2025

Rewired NAD+ metabolism promotes NF-κB-mediated oxidative stress and disrupts lipid homeostasis in liver fibrosis progression

Hiu‐Lok Ngan, Jacinth Wing‐Sum Cheu, Kenneth Kin‐Leung Kwan…·Zongwei Cai

This study identifies NAD+ metabolism rewiring as a key driver of oxidative stress and lipid dysregulation in liver fibrosis progression using multi-omics analyses in a mouse model.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky

BioinformaticsbioRxivPreprintJun 24, 2024

A machine learning and drug repurposing approach to target ferroptosis in colorectal cancer stratified by sex and KRAS

Hong Yuan Yan, Xinyi Shen, Yisha Yao…·Caroline Helen Johnson

This paper identifies sex- and KRAS-specific ferroptosis differences in CRC and explores drug repurposing for KRAS mutant tumors using multi-omics data.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky