Inhibiting EZH2 complements steroid effects in Duchenne muscular dystrophy
Eun Young Jeon, Yejin Kwak, Hyeji Kang, Hanbyeol Kim, Se Young Jin, Soojin Park, Ryeo Gyeong Kim, Dayoung Ko, Jae‐Kyung Won, Anna Cho, Inkyung Jung, Chul‐Hwan Lee, Jeongbin Park, Hyun‐Young Kim, Jong‐Hee Chae, Murim Choi
The paper investigates the role of EZH2 in Duchenne muscular dystrophy and shows that inhibiting EZH2 improves muscle phenotype in Dmd mutant mice when combined with glucocorticoids.
Science Advances · Mar 14, 2025Peer-reviewedGenetics