Developmental BiologybioRxivPreprint
Arabidopsis epigenetic factor AS2 attenuates nucleolar stress by camptothecin and establishes leaf polarity by repressing a CDK inhibitor
Ayami Nakagawa, Hidekazu Iwakawa, Hiro Takahashi…·Chiyoko Machida
The paper identifies camptothecin as a chemical modulator of AS2 function in Arabidopsis, showing its role in leaf polarity by regulating nucleolar stress and CDK inhibitor expression.
DOI 10.1101/2025.09.23.677680