Yu Lin

This study conducts the first GWAS on cell-free DNA (cfDNA) features in pregnant women, identifying 84 genetic loci and revealing causal relationships between hematological indicators and cfDNA biology.

This paper develops a machine-learning model using cfDNA fragmentation patterns to predict early-onset severe preeclampsia with high accuracy in early pregnancies and NIPT samples.

This study analyzes cell-free DNA in COVID-19 patients to show its potential for disease monitoring and tissue injury assessment.