Haiqiang Zhang

Contrasting a pretrained genomic language model's attention between case and control haplotypes ranked HBB first on chromosome 11 and recovered more known β-thalassemia variants than GWAS, without per-variant tests.

This study conducts the first GWAS on cell-free DNA (cfDNA) features in pregnant women, identifying 84 genetic loci and revealing causal relationships between hematological indicators and cfDNA biology.

This paper develops a machine-learning model using cfDNA fragmentation patterns to predict early-onset severe preeclampsia with high accuracy in early pregnancies and NIPT samples.