Author

Maxim Pyatkov

Boston UniversityORCID 0000-0002-6203-3719Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:gene regulatory network inference· 3 Organism:mouse· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Research Focus:spatial domain detection· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

David J. WaxmaniD· 3 shared Kritika Karri· 2 shared Bingtian Ye· 1 shared Christine N. Goldfarb· 1 shared Hye‐Kyung LeeiD· 1 shared Lothar G. HennighauseniD· 1 shared Naili Liu· 1 shared Oksana GavrilovaiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersGenomics

David J. WaxmanORCID

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3 papers

Recent·Most cited

GenomicsEndocrinologyPeer-reviewedMay 3, 2026

Disease-associated mutations in the STAT5B SH2 domain reprogram hepatic cholesterol and lipid metabolism

Hye‐Kyung Lee, Maxim Pyatkov, Oksana Gavrilova…·David J. Waxman

This study investigates the metabolic and gene expression effects of gain- and loss-of-function STAT5B variants in mice, revealing distinct impacts on lipid metabolism and hepatic sexual dimorphism.

DOI 10.1210/endocr/bqag057

mousebulk RNA-seq

𝕏 PostBluesky

GenomicsbioRxivPreprintOct 31, 2025

Single Nucleus MultiOmics Links Novel Transcription Factor Motifs to Murine Hepatic Sex Differences in Chromatin Accessibility and Metabolic Dysfunction-Associated Steatotic Liver Disease

Kritika Karri, Ting-Ya Chang, Maxim Pyatkov…·David J. Waxman

This study uses single-nucleus multi-omics to identify sex-specific transcription factor motifs linked to chromatin accessibility and MASLD in mouse liver.

1 citation

mousescATAC-seq

𝕏 PostBluesky

Systems BiologyEndocrinologyPeer-reviewedMay 4, 2022

Interplay between murine sex-biased gene expression and hepatic zonation revealed by single nucleus RNA sequencing

Christine N. Goldfarb, Kritika Karri, Maxim Pyatkov, David J. Waxman

This study uses single nucleus RNA sequencing to analyze sex-biased gene expression and zonation in mouse liver, revealing cell type-specific patterns and effects of GH and xenobiotic exposure.

46 citationstop 3%

mousescRNA-seq

𝕏 PostBluesky