The TARZN complex binds de novo enhancer mutations and promotes oncogenic expression in T-ALL
Nurkaiyisah Zaal Anuar, Chai Yeen Goh, Boon Haow Chua, Shi Hao Tan, Joana R. Costa, Marc R. Mansour, Takaomi Sanda, Dennis Kappei
The paper identifies the TARZN complex, which binds de novo enhancer mutations and promotes TAL1 overexpression in T-ALL through RNA methylation.
bioRxiv · Jan 24, 2025 · PreprintCell Biology