Patrick K. Quoika

This study uses smFRET-guided integrative modeling to show that Mg2+ influences RNA tertiary contact formation, revealing coexistence of bound and unbound conformations at intermediate concentrations.

This study develops a method to estimate protein melting temperatures using small-ladder replica exchange simulations, showing improved efficiency with iterative temperature ladders.

This study evaluates AF2's ability to predict protein structural ensembles by comparing its results with MD simulations and NMR data for four test proteins.

The paper highlights challenges in antibody structure prediction, emphasizing structural inaccuracies and introducing a tool to validate models.