A cystic fibrosis lung disease modifier locus harbors tandem repeats associated with gene expression
Delnaz Roshandel, Scott Mastromatteo, Cheng Wang, Jiafen Gong, Bhooma Thiruvahindrapuram, Wilson W. L. Sung, Zhuozhi Wang, Omar Hamdan, Joe Whitney, Naim Panjwani, Fan Lin, Katherine Keenan, Angela Chen, Mohsen Esmaeili, Anat Halevy, , Lisa J. Strug
The paper identifies VNTRs near SLC9A3 associated with gene expression in CF nasal epithelia and shows their utility in explaining GWAS signals.
medRxiv · Mar 28, 2022 · PreprintGenetic & Genomic Medicine