BiochemistryProtein SciencePeer-reviewed
Biochemical characterization of naturally occurring mutations in SARS-CoV-2 RNA-dependent RNA polymerase
Matěj Danda, Anna Klimešová, Klára Kušková…·Michaela Rumlová
This study examines the phenotypic effects of mutations in SARS-CoV-2 RdRp subunits using biochemical assays, finding that some mutations alter enzyme stability, complex assembly, and activity, with implications for antiviral resistance.
3 citations