Author

Anna Klimešová

University of Chemistry and Technology, PragueORCID 0000-0002-8624-1598Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Organism:virus· 1

Frequent Co-Authors

Alžběta DostálkováiD· 1 shared Aneta PagáčováiD· 1 shared Jan PrchaliD· 1 shared Klára Kušková· 1 shared Marina KapishevaiD· 1 shared Matěj DandaiD· 1 shared Michaela RumlováiD· 1 shared Tomáš RumliD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

Alžběta DostálkováORCID

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1 paper

Recent·Most cited

BiochemistryProtein SciencePeer-reviewedAug 15, 2024

Biochemical characterization of naturally occurring mutations in SARS-CoV-2 RNA-dependent RNA polymerase

Matěj Danda, Anna Klimešová, Klára Kušková…·Michaela Rumlová

This study examines the phenotypic effects of mutations in SARS-CoV-2 RdRp subunits using biochemical assays, finding that some mutations alter enzyme stability, complex assembly, and activity, with implications for antiviral resistance.

3 citations

virusproteomics

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