High-resolution de novo structure prediction from primary sequence
Ruidong Wu, Fan Ding, Rui Wang, Rui Shen, Xiwen Zhang, Shitong Luo, Chenpeng Su, Zuofan Wu, Qi Xie, Bonnie Berger, Jianzhu Ma, Jian Peng
From a single sequence, OmegaFold reaches mean LDDT 0.82 on 146 CAMEO targets, between MSA-based RoseTTAFold (0.75) and AlphaFold2 (0.86), and runs about ten times faster.
bioRxiv · Jul 21, 2022 · PreprintBioinformatics✦ In-depth digest