Author

Fan Ding

ORCID 0009-0002-1437-8218Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Assay:protein sequence· 2 Research Focus:protein design· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Research Focus:sequence-to-function modeling· 1 Approach:statistical model· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Jian PengiD· 2 shared Jianzhu MaiD· 2 shared Bonnie BergeriD· 1 shared Chenpeng Su· 1 shared Jiahan LiiD· 1 shared Qi XieiD· 1 shared Rui SheniD· 1 shared Rui Wang· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersBioinformatics

Jian PengORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintJul 21, 2022

✦ In-depth digest

High-resolution de novo structure prediction from primary sequence

Ruidong Wu, Fan Ding, Rui Wang…·Jian Peng

From a single sequence, OmegaFold reaches mean LDDT 0.82 on 146 CAMEO targets, between MSA-based RoseTTAFold (0.75) and AlphaFold2 (0.86), and runs about ten times faster.

392 citations

protein sequenceprotein structure

𝕏 PostBluesky

BioinformaticsbioRxivPreprintApr 12, 2022

Proximal Exploration for Model-guided Protein Sequence Design

Zhizhou Ren, Jiahan Li, Fan Ding…·Jian Peng

This paper introduces Proximal Exploration (PEX) and MuFacNet to improve protein sequence design by prioritizing low-mutation high-fitness mutants and predicting mutational effects.

20 citations

protein sequencedeep learning

𝕏 PostBluesky