BioinformaticsNeurobiology of AgingPeer-reviewed
Gene Age Gap Estimate (GAGE) for major depressive disorder: a penalized biological age model using gene expression
Yijie (Jamie) Li, Rayus Kuplicki, Bart N. Ford…·Brett Allen McKinney
The paper develops a gene expression-based model (GAGE) to estimate biological age gaps in MDD and finds significant associations with age and disease status.
DOI 10.1016/j.neurobiolaging.2025.01.012