Author

Jonathan B. Savitz

Laureate Institute for Brain ResearchORCID 0000-0001-8143-182XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Rayus KuplickiiD· 2 shared Aki TsuchiyagaitoiD· 1 shared Ana M. Díaz Zuluaga· 1 shared Anders Martin DaleiD· 1 shared Andriana KarukiD· 1 shared Anna Luisa KlahniD· 1 shared Annabella Di GiorgioiD· 1 shared Bart N. FordiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersNeuroscience

Rayus KuplickiORCID

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3 papers

Recent·Most cited

A Scalable Toolkit for Modeling 3D Surface-based Brain Geometry

Yanghee Im, Leila Nabulsi, Melody J.Y. Kang, Sophia I. Thomopoulos, Ana M. Díaz Zuluaga, Anders Martin Dale, Andriana Karuk, Annabella Di Giorgio, Benson Mwangi, Boris A. Gutman, Bronwyn J. Overs, Carlos López‐Jaramillo, Colm McDonald, Dan Joseph Stein, Dara M. Cannon, , for the ENIGMA Bipolar Disorder Working Group

The paper introduces a scalable toolkit for 3D surface-based brain analysis, demonstrating its utility in mapping subcortical shape variations across 21 international samples.

Lecture notes in computer science · Oct 4, 2025Peer-reviewedNeuroscience

Gene Age Gap Estimate (GAGE) for major depressive disorder: a penalized biological age model using gene expression

Yijie (Jamie) Li, Rayus Kuplicki, Bart N. Ford, Elizabeth Kresock, Leandra K. Figueroa‐Hall, Jonathan B. Savitz, Brett Allen McKinney

The paper develops a gene expression-based model (GAGE) to estimate biological age gaps in MDD and finds significant associations with age and disease status.

Neurobiology of Aging · Jul 1, 2025Peer-reviewedBioinformatics

Clinical Response to Neurofeedback in Major Depression Relates to Subtypes of Whole-Brain Activation Patterns During Training

Masaya Misaki, Kymberly D. Young, Aki Tsuchiyagaito, Jonathan B. Savitz, Salvador Martin Guinjoan

Molecular Psychiatry · Dec 26, 2024Peer-reviewedNeuroscience