Normal mammary gland development after MMTV-Cre mediated conditional PAK4 gene depletion
Parisa Rabieifar, Ting Zhuang, Tânia D. F. Costa, Miao Zhao, Staffan Strömblad
This study shows that conditional PAK4 gene depletion in mice does not impair mammary gland development, suggesting PAK4 may not be essential for normal development but could be relevant in breast cancer.
Scientific Reports · Oct 8, 2019Peer-reviewedDevelopmental Biology