Molecular BiologybioRxivPreprint
Generation and characterization of Induced Pluripotent Stem Cell models with SMAD3 mutations to study the molecular mechanism of Loeys-Dietz Syndrome Type III aneurysm formation
Nathalie P. Vroegindeweij-de Wagenaar, Janette van der Linden, Hanny Odijk…·Jeroen Essers
This study generates and characterizes induced pluripotent stem cell models with SMAD3 mutations to investigate LDS3 aneurysm formation mechanisms.
DOI 10.1101/2025.08.26.667399