Author

David Bächinger

University of ZurichORCID 0000-0002-6336-494XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Neuroscience· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Andreas H. EckhardiD· 3 shared Jennifer T. O’Malley· 2 shared Adrian DalbertiD· 1 shared Alba Escalera‐BalseraiD· 1 shared Alberto M. Parra‐PereziD· 1 shared Alison Brown· 1 shared Alvaro Gallego‐MartineziD· 1 shared Anbuselvan Dharmarajan· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersPathology

Andreas H. EckhardORCID

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3 papers

Recent·Most cited

PathologyJournal of the Association for Research in OtolaryngologyPeer-reviewedFeb 23, 2026

Integrated Histology and Molecular Profiling of Postmortem Human Auditory and Vestibular Organs via a Poly(Methyl Methacrylate)-Based Workflow

David Bächinger, Brock Peyton, Jacqueline Neubauer…·Andreas H. Eckhard

This paper introduces a rapid rPMMA workflow for molecular histopathology of calcified temporal bones, reducing processing time and costs by 90% while enabling advanced molecular assays.

2 citationstop 3%

humanwhole-genome sequencing

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NeuroscienceScientific ReportsPeer-reviewedNov 19, 2025

Hyperplastic Growth, Not Hydrostatic Distension, in Endolymphatic Hydrops in Humans Challenges the Classic View of Meniere's Disease

Corey A. Bryton, Diana M. Correa, David Bächinger…·Andreas H. Eckhard

This study challenges the traditional view of Meniere's disease by showing that endolymphatic hydrops is associated with epithelial hyperplasia rather than fluid pressure, suggesting a compensatory cellular response.

11 citations

humanmachine learning (classical)

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Genetic & Genomic MedicineClinical and Translational MedicinePeer-reviewedJun 1, 2022

Ultrarare missense and frameshift variants in the TECTA gene may involve tectorial membrane in familial Meniere disease

Pablo Román-Naranjo, Alberto M. Parra‐Perez, Alba Escalera‐Balsera…·Jose Antonio Lopez-Escamez

The paper identifies rare variants in the TECTA gene associated with familial Meniere disease and suggests their impact on tectorial membrane stability.

33 citationstop 5%

humanwhole-exome sequencing

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