Distinct mechanisms underlying extrachromosomal telomere DNA generation in ALT cancers
Junyeop Lee, Eric J. Sohn, Jina Lee, Ashley Y Cheng, Angelo Taglialatela, Alberto Ciccia, Jaewon Min
This study identifies two distinct mechanisms for generating C- and G-circles in ALT cancers, involving different origins and initiation processes for each type of extrachromosomal telomere DNA.
Nucleic Acids Research · Jul 25, 2025Peer-reviewedBiochemistry