Nasal respiration is necessary for the emergence of ketamine-induced high frequency network oscillations and behavioral hyperactivity in freely moving rats.
Jacek Wróbel, Władysław Średniawa, Gabriela Jurkiewicz, Jarosław Żygierewicz, Daniel Krzysztof Wojcik, Miles A. Whittington, Mark Jeremy Hunt
This study shows that nasal respiration is required for ketamine-induced high-frequency oscillations and hyperactivity in rats, with HFOs coupled to theta-frequency sniffing.
Scientific Reports · Nov 4, 2020Peer-reviewedNeuroscience